Critical Role of Nitrogen Blanketing in Pharmaceutical Centrifuge Operations
In pharmaceutical manufacturing, centrifuges are crucial for solvent separation but pose fire and explosion risks due to high-speed operation and flammable solvents. Nitrogen blanketing systems are vital for safety, as they reduce oxygen levels to prevent combustion.
Similarly when centrifuge is in operation continuous nitrogen blanketing is recommended for centrifuge basket as well as the bearing housing. The centrifuge inertizing skid is designed with incorporating proper interlocks to ensure safety of the Operator & maintain Quality of the product being processed.
Also, many centrifuging operations are hazardous because they feed slurries and wash liquors which contain flammable liquids. In addition, ignition sources are frequently present. To avoid fires and explosions in centrifuges, inert gas (Nitrogen) purging is commonly applied before operation begins, and inert gas blanketing is done during operation, to lower the oxygen concentration below the limiting oxygen concentration of the flammable liquid.
This communication discusses and describes three commonly used inertizing systems Monitoring by flow, Monitoring by pressure, and Monitoring by oxygen analysis.
“In addition, ignition sources are frequently present. To avoid fires and explosions in centrifuges, inert gas (Nitrogen) purging is commonly applied before operation begins, and inert gas blanketing is done during operation, to lower the oxygen concentration below the limiting oxygen concentration of the flammable liquid.”
Functions involved in Centrifuge Blanketing System
- Basket & Bearing Purging at start-up.
- Basket & Bearing Blanketing during operation.
- Basket & Bearing Pressure Relief.
- Inertization of System & Reducing O2 – Level
Special Features of Nirmal's Centrifuge Blanketing System
- Nirmal’s Centrifuge Blanketing Systems offers skid mounted ready to use solution for various fluids that are used in the Process Industries.
- These are provided with back pressure regulating valves on vent lines to minimize nitrogen consumption during continuous blanketing.
- Completely self-actuated system that can operate without auxiliary power.
- With low & High pressure indication / alarm.
- Low set point technology results in very low nitrogen consumption.
- Simple in Design & User Friendly.
- Available in Automated & Manual Option.
“Take advantage of proven Solution from Nirmal with largest install base in India and count on highly capable after sales service network across India.”